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Subscribe to ScienceAdviser to get the latest news, commentary, and research, free to your inbox daily. In the fourth century, the Greek mathematician Pappus of Alexandria praised bees for their "geometrical forethought." The hexagonal structure of their honeycomb seemed like the optimal way to partition two-dimensional space into cells of equal area and minimal perimeter — allowing the insects to cut down on how much wax they needed to produce, and to spend less time and energy building ... Science (journal) - Wikipedia Authors and reviewers must have an account to sign into our Content Tracking System (CTS) at https://cts.sciencemag.org. If you do not have an account, you will need to create one by following the prompts on the welcome page. Even a 2°C drop in the core body temperature can cause hypothermia. At this point, the effects of cold on the brain are most apparent. 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